Nobody can say for certain; Andy said he'd never shoot with Big Liam again.
The thing to remember about Andy Lee is he's been doing jerk off porn for a long time - Chris Geary, English Lads, CMNM, Triga etc. Big Liam was something of his protégé - I think Andy first brought Liam along to a shoot ~15 years ago, and it seems they were best friends off camera (and allegedly even did some escorting together). In his lulls, Andy would do circlejerk meetups (pay to attend) in hotels in London. Andy does seem to have a thing with "horsing around" with other blokes but since none of them did it as a career he'd often end up with sketchy people.
Andy started working with Triga films again in 2020, and they started selling their films on OnlyFans. Quite rapidly he realised (due to the pandemic) it'd be more lucrative to sell his own content on OnlyFans directly instead of working for a studio, and it seems like he bunged some of his friends some cash so he could have a "stable", essentially replicating the studio structure (he literally has a studio with sets now and runs a gay4pay "porn university" to get more talent). He was cool with some of the guys like Liam setting up their own little side earner.
Then Liam got really hot and also started pushing his boundaries to getting sucked off or even getting fingered on his side channel. Social media comments also started skewing towards Liam over Andy. So if we're going to speculate, it might have been Liam wanting to get more of the profits from videos he did for Andy's channel, maybe it then got heated and Liam said some insulting things about Andy, and maybe he was also trying to push to start actually fucking guys (which he started doing not too long after the split). We'll never really know, but it seems quite possible - Andy likes seeing himself as top dog and generally keeping it to "horseplay", whereas Liam fucks blokes and has pursued more aggressive monetisation models.